Pharmaceutical Technology recently interviewed Sussex Research scientists, including Dr. Brady Clark, on the role of Nuclear Magnetic Resonance Spectroscopy (NMR) and Mass Spectrometry (MS) in Glycan Synthesis and Analysis. Sussex Research is a well known specialist in carbohydrate synthesis and glycodesign with an established international reputation. As discussed in the interview, NMR and MS are vital to successful development of glycosylation in syntheses of carbohydrate-based molecules and glycans. While NMR analysis provides crucial structural information of synthesized glycans that cannot be determined in any other way, MS analysis confirms molecular weight of target synthons. In bioanalytical analyses, LC-MS/MS is ideal for quantitation of free sugars in biological matrices.
To read the full article, you are directed to PharmaTech.com (http://www.pharmtech.com/role-nmr-and-mass-spectroscopy-glycan-analysis).