Glycopeptides & Peptides

Glycopeptides are revolutionizing biomedical research and therapeutic development due to their critical roles in health and disease. Their unique glycan components enable advanced therapeutic strategies, optimized drug formulations, and deeper insights into complex biological processes. Altered glycosylation patterns make glycopeptides valuable biomarkers for early diagnosis and personalized treatment of diseases like cancer and autoimmune disorders. They are also pivotal in vaccine development and targeted cancer therapies, enhancing drug specificity and immune responses.

Beyond disease applications, glycopeptides support essential biological functions, including cell signaling, immune responses, protein stability, and interactions with pathogens. They influence gut health, metabolism, and protein properties such as solubility and thermal stability, expanding their relevance across diverse fields.

Recent developments in glycopeptides have highlighted their significant roles in human health and research, showcasing their potential in various applications:

Therapeutics: Targeted cancer treatments, enhanced vaccine efficacy, and improved drug bioavailability.

Diagnostics: Early disease detection and personalized care via glycosylation pattern analysis.

Biological Research: Insights into cell signaling, immune function, and microbiome interactions.

Nutritional Science: Dietary glycopeptides promoting gut health and immune modulation.

Advanced Research Tools: Synthetic glycopeptides aid in studying glycan-protein interactions and enable high-throughput screening for therapeutic discovery.

Cosmetic Science: Anti-aging skincare formulations improving elasticity, texture, and hydration.

We offer a diverse portfolio of glycopeptides, readily available for various applications. Explore our selection or request custom synthesis to ensure the perfect fit for your specific needs.

By Application

Browse our selection of readily available glycopeptides categorized by their application.

By Origin

Browse our selection of readily available glycopeptides categorized by their origin.

By Glycan

Explore our selection of readily available glycopeptides, organized by specific glycans.

Glycopeptide & Peptide Custom Synthesis

We are globally recognized leaders in glycopeptide synthesis, offering precisely defined and well-characterized glycosylated peptides supported by nearly two decades of expertise. We produce high-quality glycoamino acid building blocks in-house, enabling us to meet the growing demand for innovative glycopeptides.

Our expertise spans a wide array of glycopeptides and modified peptides, including N- and O-linked glycopeptides, lipopeptides, glycolipopeptides, macrocyclic peptides, and peptides labeled with fluorescent, biotin, or stable isotope markers. We specialize in challenging syntheses, such as highly branched, multi-functional, non-canonical and post-translationally modified glycopeptides, each tailored for specific biological roles.

Synthetic O-Linked Glycopeptides: Essential in cell surface and extracellular protein functions, featuring intricate glycosylation patterns like N-acetylgalactosamine (alpha-GalNAc) linked to Ser or Thr.

Synthetic N-Linked Glycopeptides: Critical for protein folding and therapeutic applications, offering enhanced in vivo stability and bioavailability.

Glycated Peptides: Implicated in conditions like diabetes and aging, these non-enzymatically modified peptides highlight our capability to tackle complex syntheses.

Custom Peptide Services: In addition to our glycopeptide services, we offer custom peptide synthesis for synthetically challenging peptides from microgram to gram scale.

We can synthesize a diverse range of structures, including linear, branched, dendrimeric, macrocyclic, multicyclic, phosphorylated, sulfated, biotinylated, fluorinated, isotope labelled and lipopeptides. Whether you need complex glycoforms, unique amino acid sequences, advanced linkers, or specific probes and labels, our team of carbohydrate and peptide specialists is ready to turn your research vision into reality.

We're here to help!

Seeking multiple distinct custom glycopeptides or peptide sequences, along with specific modifications, for your research or project? Explore our versatile synthesis services.