Collection: CD99

Cluster of differentiation 99 (CD99) is a cell surface glycoprotein known for its diverse roles in cellular adhesion, migration, and signaling. It is expressed on various cell types, including leukocytes, endothelial cells, and neurons. CD99 plays a crucial role in immune response modulation, angiogenesis, and neural development. In oncology, CD99 has been implicated in several cancers, including Ewing sarcoma and other types of soft tissue and bone tumors, where it influences tumor cell migration and invasion. Understanding CD99's functions continues to be a focus of research, aiming to uncover its potential as a therapeutic target and diagnostic marker across different disease contexts.

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