Collection: Alpha-Fetoprotein (AFP)
Alpha-Fetoprotein (AFP) is a glycoprotein produced by the fetal liver and placenta, and its glycopeptide forms have significant applications in medicine and research. Elevated AFP levels in serum, amniotic fluid, and urine are utilized as screening tests for congenital disabilities, chromosomal abnormalities, and certain adult cancers, including liver cancer and germ cell tumors. AFP glycopeptides, characterized by their distinct carbohydrate structures, offer potential for developing targeted cancer therapies and novel vaccines for cancer treatment. They also serve as key research tools for exploring protein glycosylation and its impact on disease. The varied roles of AFP glycopeptides underscore their importance in clinical and therapeutic advancements.
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TKLSQKFTKVN*FTEIQKLVLDC-NH2
where N*= Asn* = Fucα1-6GlcNAc-N-AsnInquire -
TKLSQKFTKVN(G2)FTEIQKLVLDC-NH2
where G2= G2-bi-P (NON-FUC)Inquire -
TKLSQKFTKVN(G2F)FTEIQKLVLDC-NH2
where G2= Biantennary NonasaccharideInquire -
TKLSQKFTKVN*FTEIQKLVLDC-NH2
where N* = Asn* = GlcNAcβ-N-AsnInquire
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