Sialoside Analogs

Sialoside analogs (such as R-Neu5Acα2-6LacNAc) are selective, high-affinity ligands of Siglecs. The sialic acids are chemically modified at the C-5 or C-9 positions with non-natural substituents. These ligands can be used for targeting immune cells with therapeutics encapsulated in liposomal nanoparticles decorated with Siglec ligands. We provide various sialoside analog ligands with various functional linkers depending on their intended use.
Sialoside Analogs