Product #: GA131030

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Category: Core 2 O-Glycan

Fmoc-Thr(Galβ(1-3)(GlcNAcβ(1-6))GalNAc-OH (Peracetate)

Core Glycan: Core 2 glycan is one of 4 core structures of O-GalNAc glycans of mucins. The Core 2 glycan structure is an extension of Core 3 by N-acetylglucosamine β1,6 branching and is catalyzed by three different core2 β1,6-N-acetylglucosaminyltransferase-1–3 (C2GnT-1–3).. Changes in levels of any one of these transferases may indicate celular malignancy.

Other Names: Core 2 O-Glycan on Threonine; Fmoc-Thr(β-D-Gal(1-3)[β-D-GlcNAc(1-6)]-α-D-GalNAc)-OH

References: Lee S.H., et al., J. Biol. Chem. 2010, 285, 37683-37692.

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