GP100075

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MUC1(126-149-Cys)-Tn(131,144)

MUC1 synthetic glycopeptide. Glycosylated Mucin-1 (MUC1) peptide fragment containing amino acid sequence Pro126–Gly149 (24 AA in length) from the tandem repeat (TR) region of the MUC1 protein. The fragment contains tumor-associated carbohydrate antigen (TACA), Tn antigen, O-glycosylation (α-GalNAc) at Thr131 and Thr144. The C-terminus Cysteine (amide) allows for conjugation to maleimide-functionalized carrier proteins.


Sequence:

PAPGST*APPAHGVTSAPDT*RPAPGC-NH₂
H-Pro-Ala-Pro-Gly-Ser-Thr*-Ala-Pro-Pro-Ala-His-Gly-Val-Thr-Ser-Ala-Pro-Asp-Thr*-Arg-Pro-Ala-Pro-Gly-Cys-NH2
where T* = Thr* = GalNAcα-O-Thr

MUC1(126-149-Cys)-Tn(131,144)

MUC1 synthetic glycopeptide. Glycosylated Mucin-1 (MUC1) peptide fragment containing amino acid sequence Pro126–Gly149 (24 AA in length) from the tandem repeat (TR) region of the MUC1 protein. The fragment contains tumor-associated carbohydrate antigen (TACA), Tn antigen, O-glycosylation (α-GalNAc) at Thr131 and Thr144. The C-terminus Cysteine (amide) allows for conjugation to maleimide-functionalized carrier proteins.


Sequence:

PAPGST*APPAHGVTSAPDT*RPAPGC-NH₂
H-Pro-Ala-Pro-Gly-Ser-Thr*-Ala-Pro-Pro-Ala-His-Gly-Val-Thr-Ser-Ala-Pro-Asp-Thr*-Arg-Pro-Ala-Pro-Gly-Cys-NH2
where T* = Thr* = GalNAcα-O-Thr

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  • For research and development use only
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  • Other Names

    Mucin1; Synthetic MUC-1 (di-Tn)-Cys glycopeptide

  • Technical Data

    UniProt ID: P15941

    Formula: C114H180N32O43S

    Molecular Weight: 2718.9

    Purity: >90% (HPLC)

  • Storage & Shipping

    Shipping requirement: Dry Ice

    Storage conditions: -20°C

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