GP100110

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Arg8-CGSG-MUC1(137-156)-Tn(144)

MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Gly137-His156; UniProt position 137-156, aa length 20) from the variable number tandem repeat (TR) domain. The fragment contains tumour-associated carbohydrate antigen (TACA), Tn (GalNAcα-O-Thr) at Thr144. Arg8 is conjugated at N-terminal. Arg8 is separated from the MUC1 sequence by Cys-Gly-Ser-Gly. The C-terminus is an amide.


Sequence:

RRRRRRRRCGSGGVTSAPDT*RPAPGSTAPPAH-NH2
H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Cys-Gly-Ser-Gly-Gly-Val-Thr-Ser-Ala-Pro-Asp-Thr*-Arg-Pro-Ala-Pro-Gly-Ser-Thr-Ala-Pro-Pro-Ala-His-NH2
where T* = Thr* = GalNAcα-O-Thr

Arg8-CGSG-MUC1(137-156)-Tn(144)

MUC1 (UniProt ID P15941) synthetic glycopeptide fragment (Gly137-His156; UniProt position 137-156, aa length 20) from the variable number tandem repeat (TR) domain. The fragment contains tumour-associated carbohydrate antigen (TACA), Tn (GalNAcα-O-Thr) at Thr144. Arg8 is conjugated at N-terminal. Arg8 is separated from the MUC1 sequence by Cys-Gly-Ser-Gly. The C-terminus is an amide.


Sequence:

RRRRRRRRCGSGGVTSAPDT*RPAPGSTAPPAH-NH2
H-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Arg-Cys-Gly-Ser-Gly-Gly-Val-Thr-Ser-Ala-Pro-Asp-Thr*-Arg-Pro-Ala-Pro-Gly-Ser-Thr-Ala-Pro-Pro-Ala-His-NH2
where T* = Thr* = GalNAcα-O-Thr

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      • Other Names

        Mucin1; R8-MUC1; Arg8-MUC1; Synthetic MUC-1(Tn) glycopeptide

      • Technical Data

        UniProt ID: P15941

        Formula: C146H253N63O45S

        Molecular Weight: 3643.03

        Purity: >90% (HPLC)

      • Storage & Shipping

        Shipping requirement: Dry Ice

        Storage conditions: -20°C

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