Pramlintide is a synthetic analogue of the naturally occurring neuroendocrine hormone Amylin, currently used for type I and type II diabetes patients. Amylin is also known as islet amyloid polypeptide (IAPP). Amylin (UniProt ID P10997) synthetic glycopeptide analogue fragment (Lys34-Tyr71; UniProt position 34-71; aa length 37) with GlcNAcβ at Asn69 position. The C-terminus is an amide.
K(CNTATC)ATQRLANFLVHSSNNFGPILLPPTN*VGSNTY-NH2
H-Lys-(Cys-Asn-Thr-Ala-Thr-Cys)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn*-Thr-Tyr-NH2
Where N* = Asn* = GlcNAcβ-Asn
Pramlintide is a synthetic analogue of the naturally occurring neuroendocrine hormone Amylin, currently used for type I and type II diabetes patients. Amylin is also known as islet amyloid polypeptide (IAPP). Amylin (UniProt ID P10997) synthetic glycopeptide analogue fragment (Lys34-Tyr71; UniProt position 34-71; aa length 37) with GlcNAcβ at Asn69 position. The C-terminus is an amide.
K(CNTATC)ATQRLANFLVHSSNNFGPILLPPTN*VGSNTY-NH2
H-Lys-(Cys-Asn-Thr-Ala-Thr-Cys)-Ala-Thr-Gln-Arg-Leu-Ala-Asn-Phe-Leu-Val-His-Ser-Ser-Asn-Asn-Phe-Gly-Pro-Ile-Leu-leu-Pro-Pro-Thr-Asn-Val-Gly-Ser-Asn*-Thr-Tyr-NH2
Where N* = Asn* = GlcNAcβ-Asn
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For research and development use only
UniProt ID: P10997
Formula: C185H291N53O59S2
Molecular Weight: 4265.74
Purity: >90% (HPLC)
Shipping requirement: Dry Ice
Storage conditions: -20°C
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