Product #: PE634010
Category: Mannose-6-Phosphate Ligand
Mannose-6-phosphate (M6P) glycan is a crucial signal for the trafficking of lysosomal enzymes to lysosomes and is recognized by M6P receptors (MPRs). The resulting enzyme-MPR complex is delivered to early endosomes. Development of therapeutic enzymes for lysosomal storage diseases require M6P glycans for cellular uptake and lysosomal targeting.
Other Names: M6P-PEG3-N3; M6P-PEG3-Azide; α-Man-6-phosphate-PEG3-N3; 2-[2-(2-Azidoethoxy)ethoxy]ethyl α-D-mannose-6-phosphate; (8-Azido-3,6-dioxaoctyl) α-D-mannose-6-phosphate; Azido-triethyleneglycol-functionalized M6P Ligand